The couples whose previousin vitro programs failed require special care. At INVICTA, we start the management of patients with the history of this type from examining the existing test results, performing potential additional diagnosis (full hormone profile, extended semen analysis, genetic diagnosis, etc.) and the in-depth analysis of the course of procedures relating to in vitro fertilization. Both the response to stimulation and the effects achieved on each stage in the embryology laboratory can have the incalculable diagnostic value. The effectiveness of treatment with the advanced assisted reproductive techniques can be affected in particular by: the patients’ age, their health condition, genetic factors, the manner of conducting pharmacotherapy, procedures applied in the in vitrolaboratory, circumstances of embryo culture, the manner of the female patient’s preparation for the transfer, the course of procedures, patient management at the early stage of pregnancy and many other factors./p>

The causes of failures have to be analyzed in terms of two categories of problems:

  • difficulties with getting pregnant
  • difficulties with maintaining pregnancy.

In the first case, the most common problems include:

  • poor or abnormal reaction to stimulation – it can be related, among others, to low ovarian reserve, individual predispositions, concomitant morbidities, inappropriate selection of protocol and medications.
  • poor quality of embryos – caused by the developmental disorders occurring (a) already in the first days following fertilization (suspected egg cell abnormalities) or (b) from day 3 of culture (suspected semen abnormalities)
  • absence of pregnancy in spite of obtaining embryos with proper morphology – resulting from (a) genetic factors, (b) problems with implantation which may emerge in connection with hormone deficiencies, immune disorders, abnormal mucosal structure, etc.

At INVICTA, the patients who have experienced failed attempts at in vitro fertilization will receive:

  • consultation dedicated to the thorough evaluation of the previously conducted tests and previous IVF procedures,
  • access to special tests targeted at the identification of the cause of failures,
  • consultations with specialists in many disciplines, including genetics, immunology, endocrinology, oncology, psychology, etc.
  • possibility to use embryological procedures enhancing the effectiveness of the treatment and selected to suit individual patient needs – they are proposed with regard to specific diagnosed disorders with the aim to improve the course of certain processes,
  • possibility to carry out the additional innovative genetic diagnosis PGS/PGD NGS of embryos in the course of in vitro program – its performance significantly increases the rate of successful implantations, normally developing pregnancies and births of healthy children.

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Published: 5 November 2015 Updated: 4 April 2017