(Functional fine, Acrosome activated, Morphologically Selected sperm Injection)
This technique allows to introduce to the egg cell a sperm cell with a thoroughly evaluated morphology (like in IMSI-MSOME technique) and in addition assessed intravitally for the risk of DNA fragmentation. The technique allows to reduce the risk of selecting a spermatozoon with the presence of aneuploidies. This method is recommended for patients with confirmed teratozoospermia, abnormal sperm morphology confirmed in semen analysis performed with the use of HOS (hypo-osmotic swelling) and MSOME technique, and abnormal sperm DNA fragmentation test results.